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Blend CJC 1295 NO DAC 5mg with Ipamorelin 5mg

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£135.95

Buy 2 Get 1 Free Blend CJC 1295 NO DAC 5MG with Ipamorelin 5mg

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Description

Buy 2 Get 1 Free Blend CJC 1295 NO DAC 5MG with Ipamorelin 5MG :

Unit Size 10 mg/vial
Unit Quantity 1 vial
Purity (Mass Spectrometry and UV) 99.75%
Nominal Target: 5 mg CJC 1295 NO DAC + 5 mg Ipamorelin
Sequence (CJC 1295 NO DAC) H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu- Ser-Ala-Arg-Lys-Leu–Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Sequence (IPAMORELIN) Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molecular Formula
(CJC 1295 NO DAC)
C152H252N44O42
Molecular Formula (IPAMORELIN) C38H49N9O5
Appearance Lyophilized White Powder
Source Chemical Synthesis
Storage Lyophilized Blend CJC 1295 NO DAC with Ipamorelin is stable
at roomTemperature for 90 days, however it is best to store in a freezer
below – 8c for any extended period of time.
Terms The products we offer are intended for laboratory
research use only. Please familiarize yourself with
our terms of service prior to ordering.

Blend CJC-1295 NO-DAC 5mg with Ipamorelin 5mg

All content and product information provided on this website are for informational and educational research purposes only. Products are not intended for human or animal consumption, diagnostic use, or therapeutic use.
View Research Overview & References

This blend combines two synthetic peptides for use in in vitro and in vivo (animal) laboratory research on growth-related signaling. Both peptides are analogs of human growth hormone-releasing hormone (GHRH) and share the first 29 amino acids of the 44-amino-acid sequence found in GHRH.1,2

Animal Model Research

Animal studies have examined CJC-1295 and Ipamorelin’s effects on growth hormone (GH) release compared to control groups.2,3 CJC-1295 has been studied for its effects on insulin-like growth factor 1 (IGF-1) release in various animal models.4 Research on Ipamorelin has examined its role in bone formation markers. An 8-week study in rats demonstrated increases in bone mineral content following administration of Ipamorelin, GH, and related peptides, as measured by post-mortem bone scans.5

Peptide Stability Research

CJC-1295 is studied for its pharmacokinetic and pharmacodynamic properties relative to intrinsic GHRH. The modification of the amino acid sequence in CJC-1295 NO-DAC is associated with reduced degradation by peptidase enzymes, relevant to research on peptide stability.4

Combined Research Applications

The combination of CJC-1295 and Ipamorelin is studied for its effects on multiple signaling systems, including GH-related signaling, metabolic pathways, immune-related signaling, insulin regulation, and cell differentiation, making it a research tool for investigating growth-related and metabolic signaling in a controlled laboratory environment.

Important Notice

These peptides are synthesized, combined, and distributed strictly for in vitro and in vivo (animal) research purposes only. They are not intended for human or animal consumption, medical use, diagnostic use, or any application outside of laboratory research, and have not been evaluated for safety or efficacy in humans or animals.

Product Information

This combination is provided as a white lyophilized powder, with a concentration of 10 mg per vial (5 mg of each peptide).

References

1. Matsoukas MT, Spyroulias GA. Dynamic properties of the growth hormone-releasing hormone receptor (GHRHR) and molecular determinants of GHRH binding. Mol Biosyst. 2017;13(7):1313-1322.
2. Raun K et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998 Nov;139(5):552-61.
3. Jetté L et al. Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. 2005;146(7):3052-8.
4. Campbell RM et al. Enhanced stability and potency of novel growth hormone-releasing factor (GRF) analogues derived from rodent and human GRF sequences. Peptides. 1994;15(3):489-95.
5. Svensson J et al. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats. J Endocrinol. 2000 Jun;165(3):569-77.

Certificate of Analysis (COA) and third-party lab reports are available on request. Please contact our team for documentation specific to your lot/batch.

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