Description
Buy Bulk CJC-1295 W-DAC 2mg (No Promo Codes):
| Unit Size | 2 mg/vial |
| Unit Quantity | 1 vial |
| Purity (Mass Spectrometry and UV) | 96.70% |
| Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg |
| Molecular Formula | C165H269N47O46 |
| Appearance | Lyophilized White Powder |
| Source | Chemical Synthesis |
| Storage | Lyophilized CJC 1295 DAC is Stable at room Temperature for 90 days, however it is best to store in a freezer below – 8c for any extended period of time. |
| Terms | The products we offer are intended for laboratory research use only. Please familiarize yourself with our terms of service prior to ordering. |
CJC-1295 W-DAC 2mg (Bulk)
View Research Overview & References
CJC-1295 with DAC is a synthetic analog of growth hormone-releasing hormone (GHRH), studied in laboratory research to investigate growth hormone-related signaling pathways. This peptide includes a drug affinity complex (DAC) that binds to serum albumin, a structural modification studied for its relevance to extended stability profiles in laboratory research settings.1
Animal Model Research
Animal model studies have examined CJC-1295’s effects on insulin-like growth factor-I (IGF-I) levels over extended periods following single administration.2 In an animal model study using GHRH-deficient mice, researchers examined CJC-1295’s effects on GH release patterns and growth-related metrics.3 Research has also examined CJC-1295’s relevance to studies of growth hormone pulsatility and hormone pathway signaling.1
Reproductive Physiology Research
Separate research has examined the general relationship between growth hormone and follicle-stimulating hormone (FSH)-induced differentiation in cultured rat ovarian granulosa cells, contributing background context for research into growth hormone-related signaling in endocrine and reproductive physiology.4
Product Information
CJC-1295 with DAC is available as a lyophilized powder at a concentration of 2 mg per vial, available in bulk quantity.
Important Notice
CJC-1295 with DAC is intended strictly for in vitro and in vivo (animal) laboratory research only and is not approved for human or veterinary use. All handling and experimentation must occur in compliance with applicable laboratory research protocols, and this product has not been evaluated for safety or efficacy in humans or animals.
References
1. Jetté L, et al. Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. 2005 Jul;146(7):3052-8.
2. Benquet C, Castaigne JP, Pham K, Robitaille M, Frohman LA. CJC-1295 (DAC-GRF), a long-acting GRF analog, enhances pulsatile GH secretion, increases IGF-1 levels, and restores linear growth [Abstract]. 86th Annual Meeting of The Endocrine Society, 2004, p. P3-109.
3. Alba M, et al. Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse. Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1290-4.
4. Jia XC, Kalmijn J, Hsueh AJ. Growth hormone enhances follicle-stimulating hormone-induced differentiation of cultured rat granulosa cells. Endocrinology. 1986 Apr;118(4):1401-9.
