Description
Buy 1 Get 1 Free SNAP-8 10MG :
| Unit Size | 10 mg/ vial |
| Unit Quantity | 1 vial |
| Purity (Mass Spectrometry and UV) | 99.86% |
| Sequence | Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 |
| Molecular Formula | C41H70N16O16S |
| Appearance | Lyophilized White Powder |
| Source | Chemical Synthesis |
| Storage | Lyophilized SNAP-8 is stable at room Temperature for 90 days, however it is best to store in a freezer below – 8c for any extended period of time. |
| Terms | The products we offer are intended for laboratory research use only. Please familiarize yourself with our terms of service prior to ordering. |
SNAP-8 10mg
View Research Overview & References
SNAP-8, also known as acetyl glutamyl heptapeptide-1, is a synthetic peptide studied in laboratory research. Composed of 8 amino acids with a molecular weight of 1074.5 g/mol, SNAP-8 is based on the N-terminal sequence of the SNAP-25 peptide, a protein involved in the SNARE complex and vesicle fusion machinery.
Mechanism of Action Research
In laboratory research, SNAP-8 is studied for its interaction with the SNARE complex, specifically its effects on syntaxin and synaptobrevin, proteins involved in cellular transport and vesicle fusion. Research has examined how this peptide affects SNARE complex stability, relevant to studies of neurotransmitter release mechanisms.1
Animal and Cell Model Research
Laboratory studies have examined SNAP-8 in models relevant to vesicle docking and secretory mechanisms, including research on peptides that mimic the C-terminal sequence of SNAP-25 in secretory cell models.2 Molecular modeling research has also examined the mechanism by which peptides of this class inhibit synaptotagmin-SNARE interactions.3
Important Notice
SNAP-8 is intended exclusively for in vitro laboratory research and must not be used on humans or animals under any circumstances. This product is not approved for any human or animal use, and has not been evaluated for safety or efficacy in humans or animals.
Product Information
Blue Sky Peptide’s SNAP-8 is available in a lyophilized white powder form with a concentration of 10 mg per vial.
References
1. Han J, Pluhackova K, Bockmann RA. The Multifaceted Role of SNARE Proteins in Membrane Fusion. Front Physiol. 2017;8:5.
2. Gutierrez LM, Viniegra S, Rueda J, et al. A Peptide That Mimics the C-terminal Sequence of SNAP-25 Inhibits Secretory Vesicle Docking in Chromaffin Cells. J Biol Chem. 1997;272(5):2634-9.
3. Wongrattanakamon P, Nimmanpipug P, Sirithunyalug B, Jiranusornkul S. Molecular modeling elucidates the cellular mechanism of synaptotagmin-SNARE inhibition: a novel plausible route to anti-wrinkle activity of botox-like cosmetic active molecules. Mol Cell Biochem. 2018;42:97-109.
